Penile Injections for Erectile Dysfunction

When oral therapy is not effective, penile injections for erectile dysfunction my be an option.

One option many men find very effective is penile injections, also known as ICI or intracavernosal injections.  This form of treatment involves placing medicine directly into the penis through a tiny needle, usually resulting in a firm erection in about 5-10 minutes.

Advantages                                   Disadvantages
Effective for many men                    Mild pain with injection
Firm erections                                 Medication must be kept refrigerated
Quick response                               Risk of Priapism (prolonged painful erection)
The Dallas Center for Pelvic Medicine Penile Injection Protocol is designed to minimize the cost of treatment and also minimize the risk of priapism.  Priapism is a condition where an erection is sustained for a prolonged period of time (several hours) which causes pain.  Priapism occurs with penile injection treatments in about 6% of cases and responds to medical treatment, but if left untreated it can cause permanent damage to the penis.  For this reason any man experiencing an erection for more than 2-3 hours should notify his doctor immediately so that appropriate treatment can be given.

The Dallas Center for Pelvic Medicine Penile Injection Protocol begins when a patient is given a prescription, usually for a medicine called prostaglandin E2.  After filling the prescription, the patient returns with the medicine to the Dallas Center for Pelvic Medicine where he is taught how to administer the medicine in the appropriate dose.
Using the lowest dose that is still effective is important to minimize the risk of priapism.
Our courteous and caring staff will work with each man until they are comfortable administering the medicine and we will also provide detailed dosage and administration instructions for use at home.

Sometimes, if a single medicine is not effective a combination of 2 or 3 medications (called Bi-mix or Tri-mix) is mixed and used in a single dose.

If penile injections are not effective, or a man does not care for this method of treatment, other options to treat erectile dysfunction include Vacuum Erection Device (VED) or a penile implant.

Sexual Dysfunction

  • Female Sexual Dysfunction
    • Low Sexual Desire
    • Sexual Arousal Disorder
    • Orgasmic Disorder
    • Cosmetic Procedures
    • Vaginal Rejuvenation
  • Male Sexual Dysfunction
    • Low libido
    • Delayed Ejaculation
    • Peyronie’s Disease


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